![]() Compared with AqCHX, eyes receiving PI had a greater mean pain score immediately after injection (1.44 vs. The mean patient age was 68 years (range, 39–92), and 30 of 50 (60%) were male. Results: A total of 100 eyes of 50 patients were included. Microbial swab cultures of the conjunctiva both before instillation of topical antisepsis and 10 minutes after IVIs were given. Each eye was assessed using a standardized quantitative grading system of corneal epitheliopathy (ocular staining score). Main Outcome Measures: After IVIs, participants rated their pain (Wong-Baker, scale 0–10) for each eye 1 minute after PI or AqCHX instillation and 1 day after the procedure. ![]() ![]() Both eyes received topical proparacaine 0.5%. Methods: Each patient had 1 eye randomized to PI or AqCHX, and the second eye received the other agent. Participants: Patients receiving same-day bilateral intravitreal anti–vascular endothelial growth factor (VEGF) injections. Design: Prospective single-center, randomized clinical trial. We compared patient pain scores, ocular surface characteristics, and antimicrobial efficacy between PI 5% and AqCHX 0.1% during IVIs. Aqueous chlorhexidine (AqCHX) has been described as a possibly better tolerated antimicrobial for ophthalmic procedures. Although PI is generally well tolerated, it can be associated with significant ocular irritation. Purpose: Topical povidone-iodine (PI) is widely used as an ocular surface antiseptic for intravitreal injections (IVIs).
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |